What is KS Youden

What is KS Youden

Hi mmehanna , this post could help to answer your question:Any value below 50% denote an overall lack of the diagnostic test to detect either disease or.It is prominently used in the fields of medical research for the purpose of quality assessment.Because you modeled a category response, the default fit statistic is the ks (youden) value.The receiver operating characteristic (roc) curve is used to evaluate a biomarker's ability for classifying disease status.

It is doubtful whether this cost ratio truly represents the decision.This statistical technique involves both normal and abnormal controls and graphically helps to differentiate between systematic and random errors.The youden index (j), the maximum potential effectiveness of a biomarker, is a common summary measure of the roc curve.Youden's j statistic (also called youden's index) is a single statistic that captures the performance of a dichotomous diagnostic test.

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Discovery of an autoantibody signature for the early diagnosis of knee osteoarthritis: data from the Osteoarthritis Initiative

Sensitivity, specificity and positive predictive value and negative predictive value were also estimated by the Youden Index to determine the validity and security of the models, and receiver ...

Derivation and Validation of a Novel Cardiac Intensive Care Unit Admission Risk Score for Mortality

Each continuous predictor variable from this multivariable model was converted to a categorical variable based on values above or below the optimal cutoff for each variable, defined as the highest ...

LEF1: a highly specific marker for the diagnosis of chronic lymphocytic B cell leukaemia/small lymphocytic B cell lymphoma

The relevant diagnostic cut-off value for LEF1 positivity determined by the Youden's index was 10% (specificity 92%, sensitivity 70%). The majority of CLL cases (70%) expressed LEF1. Eighteen per cent ...

Derivation and Validation of a Novel Cardiac Intensive Care Unit Admission Risk Score for Mortality

Each continuous predictor variable from this multivariable model was converted to a categorical variable based on values above or below the optimal cutoff for each variable, defined as the highest ...

Elevated Plasma Complement C1q Levels Contribute to a Poor Prognosis After Acute Primary Intracerebral Hemorrhage: A Prospective Cohort Study

Using maximum Youden method, plasma C1q levels > 270.11 mg/l distinguished patients at risk of poor prognosis at 3 months with 56.52% sensitivity and 94.55% specificity. Meanwhile, the prognostic ...

Outcomes of upper gastrointestinal cancer screening in high-risk individuals: a population-based prospective study in Northeast China

Sensitivity, specificity, Youden Index and receiver operating characteristic (ROC) curve analysis were used to evaluate the diagnostic power of the high-risk assessment based on the Harvard Risk Index ...

Histopathological analysis of retrieved thrombi from patients with acute ischemic stroke with malignant tumors

The optimal threshold cut-off values were determined at the point on the ROC curve for which Youden’s index (sensitivity + (100% – specificity)) was at a maximum. The adjusted ORs and 95% CIs of ...

A panel of nine cerebrospinal fluid biomarkers may identify patients with atypical parkinsonian syndromes

Based on the ROC analysis the best cut-off values for the CSF markers were determined from the highest Youden's index.24 Correlations between biomarkers were obtained using the Spearman rank ...

Predictors of postoperative acute exacerbation of interstitial lung disease: a case–control study

The Youden index25 was used to estimate the optimal cut-off value for the prediction of postoperative AE. We further investigated the prevalence of the positive predictors in the original population ...

Association between total dose of ritodrine hydrochloride and pulmonary oedema in twin pregnancy: a retrospective cohort study in Japan

We used the Youden index,20 which describes the maximum vertical distance between the ROC curve and the diagonal or chance line, to define the optimal cut-off value. All analyses were performed using ...

Diagnostic Value of Cardiopulmonary Ultrasound in Elderly Patients With Acute Respiratory Distress Syndrome

1.2.1 A Phillips EPIQ5 ultrasonic diagnostic apparatus was used. An abdominal convex array probe (Frequency 1–5 MHz) was used for the lung ultrasound examination; A phased array probe (frequency ...

Annual Trends in the Incidence and Prevalence of Alzheimer's Disease in South Korea: A Nationwide Cohort Study

The cut-off age for diagnosing AD was defined as the age of the patient's highest Youden index. In this study, the incidence and prevalence of AD in the Korean population aged 40 years or older showed ...